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Dopexamine hydrochloride

CAS No. 86484-91-5

Dopexamine hydrochloride ( FPL60278AR )

产品货号. M22574 CAS No. 86484-91-5

Dopexamine Hydrochloride 是一种 β2-肾上腺素能受体激动剂。 Dopexamine 是一种多巴胺类似物,可刺激 β-肾上腺素能受体以及多巴胺 1 和 2 受体,从而产生一些血管舒张作用。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥915 有现货
10MG ¥1442 有现货
25MG ¥3013 有现货
50MG ¥4504 有现货
100MG ¥6342 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Dopexamine hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Dopexamine Hydrochloride 是一种 β2-肾上腺素能受体激动剂。 Dopexamine 是一种多巴胺类似物,可刺激 β-肾上腺素能受体以及多巴胺 1 和 2 受体,从而产生一些血管舒张作用。
  • 产品描述
    Dopexamine hydrochloride is a β2-adrenergic receptor agonist. ?Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors.?Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow.(In Vitro):Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.
  • 体外实验
    Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.
  • 体内实验
    ——
  • 同义词
    FPL60278AR
  • 通路
    Angiogenesis
  • 靶点
    Adrenergic Receptor
  • 受体
    β2-adrenergic receptor
  • 研究领域
    Cancer
  • 适应症
    Oral Cancer|Head and Neck Cancer;Free Flap;Hypotension

化学信息

  • CAS Number
    86484-91-5
  • 分子量
    429.42
  • 分子式
    C22H34Cl2N2O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 100 mg/mL (232.87 mM)
  • SMILES
    Cl.Cl.Oc1ccc(CCNCCCCCCNCCc2ccccc2)cc1O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Bangash MN, et al. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. Crit Care. 2013 Mar 28;17(2):R57.
产品手册
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